These two peptides stimulate growth hormone release through two independent receptor pathways : CJC-1295 activates GHRH receptors the same pathway used by your body's natural growth hormone-releasing hormone Ipamorelin activates ghrelin receptors (GHS-R) an entirely separate signaling pathway on the pituitary Stimulating both pathways simultaneously produces a synergistic growth hormone response the combined GH output is significantly greater than the sum of each peptide individually
In summary, this investigation provides early evidence that the combination of GHRP-6, GHRP-2, and sermorelin can increase IGF-1 and testosterone levels in hypogonadal men already on testosterone therapy, while maintaining other hormones largely unchanged
AOD-9604 is a modified fragment of human growth hormone (specifically amino acids 176-191) that was developed to isolate the fat-reducing properties of growth hormone while eliminating the metabolic side effects
PMID: 13 AppelmanBCharltonBTGouldingRPKerkhoffTJBreedveldEANoortWet al
Ipamorelin Next up is Ipamorelin
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