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The most common side effects of tirzepatide include: nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, indigestion, injection site reactions, feeling tired, allergic reactions, belching, hair loss, and heartburn

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These disturbances, often influenced by intricate genetic determinants, can trigger multiple forms of programmed death in dopaminergic neurons, among which ferroptosis plays a significant role (119, 124)

A newly discovered organelle extrusion mechanism facilitates the elimination of endocytosed nanoparticles from the kidneys and may minimize the nephrotoxicity of future nanomedicines

doi: 10.1093/eurheartj/ehab724.0475/6394642 43 MakarT